​A new study led by ACS researchers shows that early-onset colorectal cancer (CRC) incidence rates are rising in 27 of 50 countries/territories worldwide, 20 of which have either exclusive or faster increases for early-onset disease. ​

In 14 countries, including the United States, rates are increasing in young adults while stabilizing in those 50 years and older. The research is published in the journal The Lancet Oncology.

“The increase in early-onset colorectal cancer is a global phenomenon,” said Dr. Hyuna Sung, senior principal scientist, cancer surveillance research at the American Cancer Society and lead author of the study. ​

“The global scope of this concerning trend highlights the need for innovative tools to prevent and control cancers linked to dietary habits, physical inactivity, and excess body weight. Ongoing efforts are essential to identify the additional factors behind these trends and to develop effective prevention strategies tailored to younger generations and local resources worldwide,” added Sung. “Raising awareness of the trend and the distinct symptoms of early-onset colorectal cancer (e.g., rectal bleeding, abdominal pain, altered bowel habits, and unexplained weight loss) among young people and primary care providers can help reduce delays in diagnosis and decrease mortality.”

Other ACS researchers contributing to the study include Rebecca Siegel, Chenxi Jiang, and senior author Dr. Ahmedin Jemal.

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